WLSEAGPVVTVRALRGTGSW

Names

[ CAS No. ]:
771479-86-8

[ Name ]:
WLSEAGPVVTVRALRGTGSW

Biological Activity

[Description]:

WLSEAGPVVTVRALRGTGSW is a cardiomyocyte specific peptide. WLSEAGPVVTVRALRGTGSW-expressing exosomes can improve specific uptake by cardiomyocytes, decrease cardiomyocyte apoptosis, and enhance cardiac retention following intramyocardial injection in vivo[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cardiovascular Disease

[References]

[1]. McGuire MJ, et, al. In vitro selection of a peptide with high selectivity for cardiomyocytes in vivo. J Mol Biol. 2004 Sep 3;342(1):171-82.

[2]. Mentkowski KI, et, al. Exosomes Engineered to Express a Cardiomyocyte Binding Peptide Demonstrate Improved Cardiac Retention in Vivo. Sci Rep. 2019 Jul 11;9(1):10041.

Chemical & Physical Properties

[ Molecular Formula ]:
C97H152N28O27

[ Molecular Weight ]:
2142.42


Related Compounds

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