2-(pentylamino)acetamide,hydrochloride
Names
[ CAS No. ]:
76990-85-7
[ Name ]:
2-(pentylamino)acetamide,hydrochloride
[Synonym ]:
Milacemide HCl
CP 1552S
Milacemide hydrochloride
Chemical & Physical Properties
[ Boiling Point ]:
264.1ºC at 760 mmHg
[ Molecular Formula ]:
C7H17ClN2O
[ Molecular Weight ]:
180.67600
[ Flash Point ]:
113.5ºC
[ Exact Mass ]:
180.10300
[ PSA ]:
56.11000
[ LogP ]:
2.59410
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AC7055000
- CHEMICAL NAME :
- Acetamide, 2-(pentylamino)-, hydrochloride
- CAS REGISTRY NUMBER :
- 76990-85-7
- LAST UPDATED :
- 199406
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C7-H16-N2-O.Cl-H
- MOLECULAR WEIGHT :
- 180.71
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5011 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 266,239,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 420 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,716,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2300 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - food intake (animal)
- REFERENCE :
- ATDAEI Acute Toxicity Data. Journal of the American College of Toxicology, Part B. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1- 1990- Volume(issue)/page/year: 1,716,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 339 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 266,239,1983