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1-Butylpyrrolidine

Names

[ CAS No. ]:
767-10-2

[ Name ]:
1-Butylpyrrolidine

[Synonym ]:
Pyrrolidine,1-butyl
MFCD00003184
1-Butylpyrrolidine
N-(n-butyl)-pyrrolidine
EINECS 212-179-4
1-butyl-pyrrolidine
Pyrrolidine, 1-butyl-
1-Butyl-pyrrolidin
1- Butyl pyrrolidine
N-butyl-pyrrolidine
N-n-butyl azacyclopentane
butylpyrrolidine

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
154.7±3.0 °C at 760 mmHg

[ Molecular Formula ]:
C8H17N

[ Molecular Weight ]:
127.227

[ Flash Point ]:
41.8±3.5 °C

[ Exact Mass ]:
127.136101

[ PSA ]:
3.24000

[ LogP ]:
2.35

[ Vapour Pressure ]:
3.1±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.453

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UX9800000
CHEMICAL NAME :
Pyrrolidine, 1-butyl-
CAS REGISTRY NUMBER :
767-10-2
BEILSTEIN REFERENCE NO. :
0102915
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C8-H17-N
MOLECULAR WEIGHT :
127.26
WISWESSER LINE NOTATION :
T5NTJ A4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
51 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Behavioral - muscle contraction or spasticity
REFERENCE :
INHEAO Industrial Health. (National Institute of Industrial Health, 6-21-1 Nagao, Tama-ku, Kawasaki, 213 Japan) V.1- 1963- Volume(issue)/page/year: 4,63,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
820 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
INHEAO Industrial Health. (National Institute of Industrial Health, 6-21-1 Nagao, Tama-ku, Kawasaki, 213 Japan) V.1- 1963- Volume(issue)/page/year: 4,63,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
37 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Behavioral - muscle contraction or spasticity
REFERENCE :
INHEAO Industrial Health. (National Institute of Industrial Health, 6-21-1 Nagao, Tama-ku, Kawasaki, 213 Japan) V.1- 1963- Volume(issue)/page/year: 4,63,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
57 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Behavioral - muscle contraction or spasticity
REFERENCE :
INHEAO Industrial Health. (National Institute of Industrial Health, 6-21-1 Nagao, Tama-ku, Kawasaki, 213 Japan) V.1- 1963- Volume(issue)/page/year: 4,63,1966

Safety Information

[ Symbol ]:

GHS02, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H301 + H311

[ Precautionary Statements ]:
P280-P301 + P310-P312

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R10;R24/25

[ Safety Phrases ]:
S16-S36/37-S45

[ RIDADR ]:
UN 2929 6.1/PG 2

[ WGK Germany ]:
2

[ RTECS ]:
UX9800000

[ Packaging Group ]:
III

[ Hazard Class ]:
3.2

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Optimised microwave-assisted synthesis of methylcarbonate salts: a convenient methodology to prepare intermediates for ionic liquid libraries. Holbrey JD, et al.

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J. Chem. Sci. 125(6) , 1511-15, (2013)


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