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RU 28318, potassium salt

Names

[ CAS No. ]:
76676-34-1

[ Name ]:
RU 28318, potassium salt

[Synonym ]:
Potassium oxprenoate
Oxprenoate
Oxprenoate Potassium

Biological Activity

[Description]:

Oxprenoate potassium is a potent mineralocorticoid (MR) antagonist. Oxprenoate potassium accentuates DEX (dexamethasone)-induced apoptosis[1].

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> Metabolic Enzyme/Protease >> Mineralocorticoid Receptor

[References]

[1]. Crochemore C, et al. Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation. Mol Psychiatry. 2005 Aug;10(8):790-8.

Chemical & Physical Properties

[ Boiling Point ]:
569.3ºC at 760 mmHg

[ Molecular Formula ]:
C25H37KO4

[ Molecular Weight ]:
440.65700

[ Flash Point ]:
312.2ºC

[ Exact Mass ]:
440.23300

[ PSA ]:
77.43000

[ LogP ]:
3.80570

Related Compounds