Broussonin C

Names

[ Name ]:
Broussonin C

[Synonym ]:
4-{3-[4-Hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]propyl}-1,3-benzenediol
1,3-Benzenediol, 4-[3-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]propyl]-

Biological Activity

[Description]:

Broussonin C is a competitive inhibitor of Tyrosinase that can be isolated from Broussonetia kazinoki. Broussonin C inhibits monophenolase and diphenolase with IC50s of 0.43 and 0.57 μM, respectively[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Metabolic Enzyme/Protease >> Tyrosinase

[References]

[1]. Baek YS, et al. Rengasamy R, Yang MS, Park KH. Tyrosinase inhibitory effects of 1,3-diphenylpropanes from Broussonetia kazinoki. Bioorg Med Chem. 2009 Jan 1;17(1):35-41.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
499.3±14.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₄O₃

[ Molecular Weight ]:
312.40

[ Flash Point ]:
229.3±14.7 °C

[ Exact Mass ]:
312.172546

[ PSA ]:
60.69000

[ LogP ]:
4.98

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.611

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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