Di(N-desethyl) Amiodarone Hydrochloride

Names

[ Name ]:
Di(N-desethyl) Amiodarone Hydrochloride

[Synonym ]:
Amiodarone Impurity 9

Biological Activity

[Description]:

Di-N-desethyl Amiodarone hydrochloride is a metabolite of Amiodarone (HY-14187). Di-N-desethyl Amiodarone hydrochloride is a strong inhibitor of the respiratory chain[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Autophagy >> Autophagy

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[References]

[1]. Anja Zahno,et al. The role of CYP3A4 in amiodarone-associated toxicity on HepG2cells. Biochem Pharmacol. 2011 Feb 1;81(3):432-41.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₂ClI₂NO₃

[ Molecular Weight ]:
625.67

[ Exact Mass ]:
624.93800

[ PSA ]:
65.46000

[ LogP ]:
7.05540

Related Compounds

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