EN106

Names

[ Name ]:
EN106

Biological Activity

[Description]:

EN106 is a potent inhibitor of FEMIB. EN106 is a cysteine-reactive covalent ligand. EN106 disrupts recognition of the key reductive stress substrate of FEM1B, FNIP1[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Henning NJ, et al. Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications. J Am Chem Soc. 2022;144(2):701-708.

Chemical & Physical Properties

[ Density]:
1.351±0.06 g/cm3(Predicted)

[ Boiling Point ]:
489.1±45.0 °C(Predicted)

[ Molecular Formula ]:
C₁₃H₁₃ClN₂O₃

[ Molecular Weight ]:
280.71

[ Storage condition ]:
-20°C

Related Compounds

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