11-trans Leukotriene E4

Names

[ Name ]:
11-trans Leukotriene E4

[Synonym ]:
(5S,6R,7E,9E,11E,14Z)-6-{[(2R)-2-Amino-2-carboxyethyl]sulfanyl}-5-hydroxy-7,9,11,14-icosatetraenoic acid
7,9,11,14-Eicosatetraenoic acid, 6-[[(2R)-2-amino-2-carboxyethyl]thio]-5-hydroxy-, (5S,6R,7E,9E,11E,14Z)-

Biological Activity

[Description]:

11-trans Leukotriene E4 is an isomer of Leukotriene E4 (LTE4). Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans Leukotriene E4 is equipotent to LTE4 in contracting guinea pig ileum[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. S Hammarström, et al. Metabolism of leukotrienes. Mol Cell Biochem. 1985 Nov;69(1):7-16.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
674.1±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₃H₃₇NO₅S

[ Molecular Weight ]:
439.609

[ Flash Point ]:
361.5±31.5 °C

[ Exact Mass ]:
439.239258

[ PSA ]:
146.15000

[ LogP ]:
5.65

[ Vapour Pressure ]:
0.0±4.7 mmHg at 25°C

[ Index of Refraction ]:
1.557

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.