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SSR125543

Names

[ CAS No. ]:
752253-39-7

[ Name ]:
SSR125543

Biological Activity

[Description]:

Crinecerfont (SSR-125543) hydrochloride is a potent, orally active, non-peptide CRF1 receptor antagonist. Crinecerfont can be used for Classic congenital adrenal hyperplasia (CAH) research[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> CFTR
Research Areas >> Metabolic Disease

[Target]

IC50: CRF1 receptor


[References]

[1]. Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia (CAHtalyst).

Chemical & Physical Properties

[ Molecular Formula ]:
C27H28ClFN2OS

[ Molecular Weight ]:
483.04000

[ Exact Mass ]:
482.15900

[ PSA ]:
53.60000

[ LogP ]:
7.51740

Related Compounds