1-(2,6-DIHYDROXY-4-METHOXYPHENYL)ETHANONE

Names

[ Name ]:
1-(2,6-DIHYDROXY-4-METHOXYPHENYL)ETHANONE

[Synonym ]:
2,6-dihydroxy-4-methoxy-1-acetobenzene
4-O-Methylphloroacetophenone
2,6-dihydroxy-acetophenone-4-methyl ether
2,6-Dihydroxy-4-methoxyacetophenone
2-acetylphloroglucinol 5-O-methyl ether
Desaspidinol-A
3'-O-demethylxanthoxylline
Acetophenone,2',6'-dihydroxy-4'-methoxy

Biological Activity

[Description]:

2,6-Dihydroxy-4-methoxyacetophenone is a phytoalexin, that can be isolated from the root tissue of Sanguisorba minor. 2,6-Dihydroxy-4-methoxyacetophenone exhibits antifungal activity. 2,6-Dihydroxy-4-methoxyacetophenone is a strong germination inhibitor on B. cinerea[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[In Vitro]

2,6-Dihydroxy-4-methoxyacetophenone 对两种非致病性真菌 Botrytis cinerea 和 Phomopsis perniciosa 具有抗真菌活性。孢子萌发的ED50分别为 45 和 410 μM[1]。

[References]

[1]. Kokubun T, et al. 2′,6′-Dihydroxy-4′-methoxyacetophenone, a phytoalexin from the roots of Sanguisorba minor. Phytochemistry, 1994, 35(2):331-333.

Chemical & Physical Properties

[ Density]:
1.284 g/cm3

[ Boiling Point ]:
356.7ºC at 760 mmHg

[ Melting Point ]:
144ºC

[ Molecular Formula ]:
C₉H₁₀O₄

[ Molecular Weight ]:
182.17300

[ Flash Point ]:
146.3ºC

[ Exact Mass ]:
182.05800

[ PSA ]:
66.76000

[ LogP ]:
1.30900

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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