Tetramethyl ammonium chloride
Names
[ CAS No. ]:
75-57-0
[ Name ]:
Tetramethyl ammonium chloride
[Synonym ]:
Methanaminium, N,N,N-trimethyl-, chloride (1:1)
tetramethyl-ammonium chloride
N,N,N-Trimethylmethanaminium chloride
tetramethyl-ammoniuchloride
TMA
50g
TMACL
Tetramethylazanium chloride
tetrametylammonium chloride
MFCD00011628
tetraminechloride
EINECS 200-880-8
anhydrous tetramethylammonium chloride
Tetramethylammonium chloride
TMAC
usafan-8
Tetramethylammoniumchlorid
Chemical & Physical Properties
[ Density]:
1,17 g/cm3
[ Melting Point ]:
>300 °C(lit.)
[ Molecular Formula ]:
C4H12ClN
[ Molecular Weight ]:
109.598
[ Exact Mass ]:
109.065826
[ Storage condition ]:
Store at RT.
[ Stability ]:
Stable. Incompatible with strong oxidizing agents, water. Hygroscopic.
[ Water Solubility ]:
>60 g/100 mL (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BS7700000
- CHEMICAL NAME :
- Ammonium, tetramethyl-, chloride
- CAS REGISTRY NUMBER :
- 75-57-0
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C4-H12-N.Cl
- MOLECULAR WEIGHT :
- 109.62
- WISWESSER LINE NOTATION :
- 1K1&1&1 &G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 125 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 69,327,1980
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD414-344
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 40 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: ORNL-5576
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 7,183,1900
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 6 mg/kg
- TOXIC EFFECTS :
- Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 7,183,1900
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 7,183,1900
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Cardiac - other changes
- REFERENCE :
- SAPHAO Skandinavisches Archiv fuer Physiologie. (Stockholm, Sweden) V.1-83, 1899-1940. For publisher information, see APSCAX. Volume(issue)/page/year: 10,201,1900 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4596 No. of Facilities: 41 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 2840 (estimated) No. of Female Employees: 1777 (estimated)
Safety Information
[ Symbol ]:
GHS06, GHS08, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H300-H311-H315-H370-H411
[ Precautionary Statements ]:
P260-P273-P280-P301 + P310 + P330-P302 + P352 + P312-P308 + P311
[ Target Organs ]:
Central nervous system
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R25;R36/37/38
[ Safety Phrases ]:
S26-S36/37-S45-S37/39-S28A-S28
[ RIDADR ]:
UN 2811 6.1/PG 2
[ WGK Germany ]:
1
[ RTECS ]:
BS7700000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
29239000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29239000
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