2-Chloro-1,1,1-Trimethoxyethane
Names
[ CAS No. ]:
74974-54-2
[ Name ]:
2-Chloro-1,1,1-Trimethoxyethane
[Synonym ]:
2-Chloro-1,1,1-Trimethoxyethane
Ethane, 2-chloro-1,1,1-trimethoxy-
MFCD00216629
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
143.2±35.0 °C at 760 mmHg
[ Molecular Formula ]:
C5H11ClO3
[ Molecular Weight ]:
154.592
[ Flash Point ]:
40.8±26.0 °C
[ Exact Mass ]:
154.039673
[ PSA ]:
27.69000
[ LogP ]:
1.84
[ Vapour Pressure ]:
6.8±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.412
MSDS
Safety Information
[ Symbol ]:
GHS02
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H226
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R10
[ Safety Phrases ]:
S16-S45
[ RIDADR ]:
UN 1993 3/PG 3
[ WGK Germany ]:
3
[ HS Code ]:
2909199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2909199090
[ Summary ]:
2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
ACS Chem. Neurosci. 4(4) , 624-34, (2013)
The transient receptor potential vanilloid subfamily member 1 (TRPV1) cation channel is known to be involved in pain nociception and neurogenic inflammation, and accumulating evidence suggests that it...
CVT-4325: a potent fatty acid oxidation inhibitor with favorable oral bioavailability.Bioorg. Med. Chem. Lett. 14 , 6017-6021, (2004)
New inhibitors of palmitoyl-CoA oxidation are based on the introduction of nitrogen heterocycles in the 'Western Portion' of the molecule. SAR studies led to the discovery of CVT-4325 (shown), a poten...
A new synthesis of 1, 2, 4-triazolin-5-ones: application to the convergent synthesis of an NK 1 antagonist. Cowden CJ, et al.Tetrahedron Lett. 41(44) , 8661-64, (2000)