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Juniferdin

Names

[ CAS No. ]:
74724-29-1

[ Name ]:
Juniferdin

Biological Activity

[Description]:

Juniferdin is an inhibitor of Protein disulfide isomerase (PDI) (IC50=3.5 μM), aiming to block HIV transmission. Juniferdin is cytotoxic, and also inhibits platelet aggregation[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

Juniferdin 导致血小板聚集的不可逆性,洗涤血小板后活性为 100%[1]。

[References]

[1]. Khodier C, et al. Identification of ML359 as a Small Molecule Inhibitor of Protein Disulfide Isomerase. 2013 Apr 12 [updated 2014 Sep 18]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–.  

Chemical & Physical Properties

[ Molecular Formula ]:
C22H30O4

[ Molecular Weight ]:
358.47100

[ Exact Mass ]:
358.21400

[ PSA ]:
66.76000

[ LogP ]:
4.77130


Related Compounds

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