Ergoline-8-beta-propionitrile, 6-methyl-alpha-(4-methyl-1-piperazinylc arbonyl)-
Names
[ CAS No. ]:
74627-31-9
[ Name ]:
Ergoline-8-beta-propionitrile, 6-methyl-alpha-(4-methyl-1-piperazinylc arbonyl)-
Chemical & Physical Properties
[ Density]:
1.204g/cm3
[ Boiling Point ]:
641.9ºC at 760 mmHg
[ Molecular Formula ]:
C24H31N5O
[ Molecular Weight ]:
405.53600
[ Flash Point ]:
342ºC
[ Exact Mass ]:
405.25300
[ PSA ]:
66.37000
[ LogP ]:
2.24548
[ Index of Refraction ]:
1.615
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KE6345210
- CHEMICAL NAME :
- Ergoline-8-beta-propionitrile, 6-methyl-alpha-(4-methyl-1-piperazinylcarbonyl)-
- CAS REGISTRY NUMBER :
- 74627-31-9
- LAST UPDATED :
- 199309
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C24-H31-N5-O
- MOLECULAR WEIGHT :
- 405.60
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Vascular - BP lowering not characterized in autonomic section
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 33,1094,1983 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 16 mg/kg
- SEX/DURATION :
- female 5 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 33,1094,1983
Related Compounds
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