Cupric chloride
Names
[ CAS No. ]:
7447-39-4
[ Name ]:
Cupric chloride
[Synonym ]:
Cupric chloride
EINECS 231-210-2
copper chloride
Coclor
Copper(2+) dichloride
cupricdichloride
MFCD00010972
Copper(2+) chloride
Copper(2+)chloride
CuCl2
Copper(II) chloride
Cupric dichloride
copper dichloride
copper (ii) chloride
Copper(II) chloride (1:2)
Cupperdichloride
copperbichloride
Chemical & Physical Properties
[ Density]:
3.386 g/mL at 25 °C(lit.)
[ Boiling Point ]:
993°C/760mmHg
[ Melting Point ]:
620 °C(lit.)
[ Molecular Formula ]:
CuCl2
[ Molecular Weight ]:
134.452
[ Exact Mass ]:
132.867310
[ Stability ]:
Stable. Reacts violently with potassium and sodium. Contact with acetylene may form explosive acetylides. Hygroscopic.
[ Water Solubility ]:
620 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GL7000000
- CAS REGISTRY NUMBER :
- 7447-39-4
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 47
- MOLECULAR FORMULA :
- Cl2-Cu
- MOLECULAR WEIGHT :
- 134.44
- WISWESSER LINE NOTATION :
- CU G2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 584 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 14700 ug/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 233 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7400 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 20 ug/m3/26W-I
- TOXIC EFFECTS :
- Blood - changes in leukocyte (WBC) count Nutritional and Gross Metabolic - changes in chlorine
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- DOSE :
- 8 ug/m3
- SEX/DURATION :
- female 1-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - extra-embryonic structures (e.g., placenta, umbilical cord) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 35 mg/kg
- SEX/DURATION :
- female 12-18 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 2 mmol/L
- REFERENCE :
- SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 198,513,1977 *** REVIEWS *** TOXICOLOGY REVIEW 85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: Cu,23,1977 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-AUSTRALIA:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-AUSTRALIA:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-BELGIUM:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-BELGIUM:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-DENMARK:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-DENMARK:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-FINLAND:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-FINLAND:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-FRANCE:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-FRANCE:TWA 1 mg(Cu)/m3;STEL 2 mg(Cu)/m3 (dust) JAN 1993 OEL-GERMANY:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-GERMANY:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-HUNGARY:TWA 0.2 mg(Cu)/m3;STEL 0.4 mg(Cu)/m3 (dust) JAN 1993 OEL-INDIA:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-THE NETHERLANDS:TWA 02 mg(Cu)/m3 (fume) JAN 1993 OEL-THE NETHERLANDS:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-THE PHILIPPINES:TWA 1.0 mg(Cu)/m3 (fume) JAN 1993 OEL-POLAND:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-RUSSIA:STEL 0.5 ppm (1 mg(Cu)/m3) (dust) JAN 1993 OEL-SWEDEN:TWA 0.2 mg(Cu)/m3 (resp. dust) JAN 1993 OEL-SWEDEN:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-SWEDEN:TWA 1 mg(Cu)/m3 (total dust) JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg(Cu)/m3;STEL 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-SWITZERLAND:TWA 1 mg(Cu)/m3;STEL 1 mg(Cu)/m3 JAN 1993 OEL-THAILAND:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-THAILAND:TWA 1 mg(Cu)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-UNITED KINGDOM:TWA 1 mg(Cu)/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9857 No. of Facilities: 1154 (estimated) No. of Industries: 20 No. of Occupations: 28 No. of Employees: 16759 (estimated) No. of Female Employees: 9684 (estimated)
Safety Information
[ Symbol ]:
GHS05, GHS07, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302 + H312-H315-H318-H410
[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R25;R36/37/38;R50/53
[ Safety Phrases ]:
S61-S57-S45-S37/39-S29-S26-S60-S36
[ RIDADR ]:
UN 3264 8/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
GL7000000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
28274990
Synthetic Route
Customs
[ HS Code ]: 28274990
Articles
Pharm. Res. 31(11) , 3106-19, (2014)
Although Cu complexes have been investigated as anticancer agents, there has been no description of Cu itself as a cancer killing agent. A stealth liposomal Cu formulation (LpCu) was studied in vitro ...
Rational Design of Photonic Dust from Nanoporous Anodic Alumina Films: A Versatile Photonic Nanotool for Visual Sensing.Sci. Rep. 5 , 12893, (2015)
Herein, we present a systematic study on the development, optimisation and applicability of interferometrically coloured distributed Bragg reflectors based on nanoporous anodic alumina (NAA-DBRs) in t...
An orphan esterase ABHD10 modulates probenecid acyl glucuronidation in human liver.Drug Metab. Dispos. 42(12) , 2109-16, (2014)
Probenecid, a widely used uricosuric agent, is mainly metabolized to probenecid acyl glucuronide (PRAG), which is considered a causal substance of severe allergic or anaphylactoid reactions. PRAG can ...