7-Acetylintermedine

Names

[ Name ]:
7-Acetylintermedine

[Synonym ]:
[(1R,7aR)-1-(acetyloxy)-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl]methyl (2S,3R)-2,3-dihydroxy-2-(propan-2-yl)butanoate
Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, [(1R,7aR)-1-(acetyloxy)-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl]methyl ester, (2S,3R)-
Acetylintermedine
[(1R,7aR)-1-Acetoxy-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl]methyl (2S,3R)-2,3-dihydroxy-2-isopropylbutanoate
Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, ((1R,7aR)-1-(acetyloxy)-2,3,5,7a-tetrahydro-1H-pyrrolizin-7-yl)methyl ester, (2S,3R)-

Biological Activity

[Description]:

7-Acetylintermedine is a hepatotoxic botanical pyrrolizidine alkaloid[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[In Vitro]

7-Acetylintermedine is positive for liver necrosis and possess hepatotoxicity alerts at their pyrroline positions[1].

[References]

[1]. Yun-Jan Wang, et al. Computational analysis for hepatic safety signals of constituents present in botanical extracts widely used by women in the United States for treatment of menopausal symptoms. Regul Toxicol Pharmacol. 2011 Feb;59(1):111-24.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
466.0±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₂₇NO₆

[ Molecular Weight ]:
341.399

[ Flash Point ]:
235.6±28.7 °C

[ Exact Mass ]:
341.183838

[ LogP ]:
0.16

[ Vapour Pressure ]:
0.0±2.6 mmHg at 25°C

[ Index of Refraction ]:
1.546

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.