Benzilic acid, 1.alpha.-H,5.alpha.-H-tropan-3.beta.-yl ester

Names

[ Name ]:
Benzilic acid, 1.alpha.-H,5.alpha.-H-tropan-3.beta.-yl ester

[Synonym ]:
Tropine benzilate
3alpha(1alphaH,5alphaH)-Tropanylbenzilat
endo-8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 2-hydroxy-2,2-diphenylacetate
Tropinbenzilat
Glypin
benzilic acid tropane-3exo-yl ester
Glipin
Benzziloyl tropein
(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(diphenyl)acetate
benzilic acid tropane-3endo-yl ester
Tropanyl benzilate
Benzilsaeure-tropan-3exo-ylester
Benzilsaeure-tropan-3endo-ylester

Chemical & Physical Properties

[ Density]:
1.23g/cm3

[ Boiling Point ]:
444.7ºC at 760mmHg

[ Molecular Formula ]:
C₂₂H₂₅NO₃

[ Molecular Weight ]:
351.43900

[ Flash Point ]:
222.7ºC

[ Exact Mass ]:
351.18300

[ PSA ]:
49.77000

[ LogP ]:
3.02880

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YM4150000

CHEMICAL NAME :: 1-alpha-H,5-alpha-H-Tropan-3-beta-ol, benzilate (ester)

CAS REGISTRY NUMBER :: 74051-39-1

LAST UPDATED :: 199012

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C22-H25-N-O3

MOLECULAR WEIGHT :: 351.48

WISWESSER LINE NOTATION :: T56 A ANTJ A1 DOVXQR&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Kidney, Ureter, Bladder - hematuria

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 14,559,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 22 mg/kg

TOXIC EFFECTS :: Behavioral - excitement Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 59,149,1938

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.