DL-THREO-DIHYDROSPHINGOSINE

[ Molecular Formula ]:
C₁₈H₃₉NO₂

[ Molecular Weight ]:
301.50800

[ Exact Mass ]:
301.29800

[ PSA ]:
66.48000

[ LogP ]:
4.84850

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Click to get detail synthetic route

Precursor

DownStream

Extracellular sphingomyelinase induces interleukin-6 synthesis in osteoblasts.

J. Cell. Biochem. 72 , 262-8, (1999)

In osteoblast-like MC3T3-E1 cells, we have recently reported that sphingosine 1-phosphate among sphingomyelin metabolites acts as a second messenger for tumor necrosis factor-alpha (TNF)-induced inter...

Sphingosine modulates interleukin-6 synthesis in osteoblasts.

J. Cell. Biochem. 70 , 338-45, (1998)

We previously reported that prostaglandin (PG)E1 and PGF2alpha induce the synthesis of interleukin-6 (IL-6) via activation of protein kinase (PK)A and PKC, respectively, in osteoblast-like MC3T3-E1 ce...

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