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3-[2-[1-(6-hydroxy-6-methylheptan-2-yl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol

Names

[ CAS No. ]:
73809-05-9

[ Name ]:
3-[2-[1-(6-hydroxy-6-methylheptan-2-yl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol

[Synonym ]:
(3s)-9,10-secocholesta-5,7,10-triene-3,25-diol
3-Epi-25-Hydroxyvitamin D3
25-Hydroxycholecalciferol
25-Hydroxy-vitamin D3
(1S,3Z)-3-[(2E)-2-[(1R,7aR)-1-(6-hydroxy-6-methylheptan-2-yl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol

Chemical & Physical Properties

[ Molecular Formula ]:
C27H44O2

[ Molecular Weight ]:
400.63700

[ Exact Mass ]:
400.33400

[ PSA ]:
40.46000

[ LogP ]:
6.73390

MSDS

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H319

[ Precautionary Statements ]:
P210-P280-P305 + P351 + P338-P337 + P313-P403 + P235

[ RIDADR ]:
UN1170 - class 3 - PG 2 - Ethanol, solution

Articles

Dietary resistant starch prevents urinary excretion of 25-hydroxycholecalciferol and vitamin D-binding protein in type 1 diabetic rats.

J. Nutr. 143(7) , 1123-8, (2013)

Diabetes is a rapidly growing epidemic affecting millions of Americans and has been implicated in a number of devastating secondary complications. We previously demonstrated that type 2 diabetic rats ...

25-hydroxvitamin D3 promotes the long-term effect of specific immunotherapy in a murine allergy model.

J. Immunol. 193(3) , 1017-23, (2014)

Calcitriol (1α,25-dihydroxyvitamin D3) is the active vitamin D metabolite and mediates immunological functions, which are relevant in allergy. Its therapeutic use is limited by hypercalcaemic toxicity...

Vitamin D deficiency impairs rituximab-mediated cellular cytotoxicity and outcome of patients with diffuse large B-cell lymphoma treated with but not without rituximab.

J. Clin. Oncol. 32(29) , 3242-8, (2014)

To investigate the impact and mechanisms of vitamin D deficiency (VDD) on the outcome of elderly patients with diffuse large B-cell lymphoma (DLBCL).Three hundred fifty-nine pretreatment 25-hydroxyvit...


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