4-Hydroxy-3-(p-tolyl)-2H-1-benzopyran-2-one
Names
[ CAS No. ]:
73791-19-2
[ Name ]:
4-Hydroxy-3-(p-tolyl)-2H-1-benzopyran-2-one
[Synonym ]:
4-hydroxy-3-p-tolyl-chromen-2-one
4-hydroxy-3-p-tolyl-2H-chromen-2-one
4-hydroxy-3-p-tolylcoumarin
4-Hydroxy-3-p-tolyl-cumarin
Chemical & Physical Properties
[ Density]:
1.324g/cm3
[ Boiling Point ]:
406.1ºC at 760 mmHg
[ Molecular Formula ]:
C16H12O3
[ Molecular Weight ]:
252.26500
[ Flash Point ]:
153.2ºC
[ Exact Mass ]:
252.07900
[ PSA ]:
50.44000
[ LogP ]:
3.47400
[ Index of Refraction ]:
1.663
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GN7648500
- CHEMICAL NAME :
- Coumarin, 4-hydroxy-3-(p-tolyl)-
- CAS REGISTRY NUMBER :
- 73791-19-2
- BEILSTEIN REFERENCE NO. :
- 1287628
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C16-H12-O3
- MOLECULAR WEIGHT :
- 252.28
- WISWESSER LINE NOTATION :
- T66 BO CVJ EQ DR D1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,29,1964