4-((4-Bromobenzyl)oxy)quinazoline

Names

[ Name ]:
4-((4-Bromobenzyl)oxy)quinazoline

[Synonym ]:
MFCD03983874

Biological Activity

[Description]:

VEGFR2-IN-2 (compound 6e) is a potent and selective VEGFR2 inhibitor with an IC50 of 19.32 nM. VEGFR2-IN-2 can be used for researching

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR

[Target]

VEGFR2:19.32 nM (IC50)

[References]

[1]. Sun J, et al. Design, synthesis, biological evaluation, and molecular modeling study of 4-alkoxyquinazoline derivatives as potential VEGFR2 kinase inhibitors. Org Biomol Chem. 2013 Nov 28;11(44):7676-86.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₁₁BrN₂O

[ Molecular Weight ]:
315.16

Related Compounds

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