N-tert-Butyl-α-(2-sulfophenyl)nitrone sodium salt
Names
[ CAS No. ]:
73475-11-3
[ Name ]:
N-tert-Butyl-α-(2-sulfophenyl)nitrone sodium salt
[Synonym ]:
N-tret-butyl-α-phenylnitrone
sodium tert-butyl(1-sulfonatobenzylidene)amine-N-oxide
MFCD00012017
sodium 2-[(tert-butylimino)methyl]benzenesulfonate N-oxide
Chemical & Physical Properties
[ Melting Point ]:
246 °C (dec.) (lit.)
[ Molecular Formula ]:
C11H14NNaO4S
[ Molecular Weight ]:
279.28800
[ Exact Mass ]:
279.05400
[ PSA ]:
94.33000
[ LogP ]:
2.92240
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
36/37/38
[ Safety Phrases ]:
26-37/39
[ RIDADR ]:
NONH for all modes of transport
Articles
Free Radic. Biol. Med. 28(4) , 597-603, (2000)
N-tert-butyl-alpha-phenylnitrone (PBN), a widely used nitrone-based free radical trap was recently shown to prevent acetylcholinesterase (AChE) inhibitors induced muscle fasciculations and brain seizu...
Effects of cytisine on hydroxyl radicals in vitro and MPTP-induced dopamine depletion in vivo.Eur. J. Pharmacol. 360(2-3) , 155-63, (1998)
The potential new iron-chelator cytisine and the radical scavenger N-tert-butyl-alpha-(2-sulfophenyl) nitrone (S-PBN) were incubated in a Fenton system and hydroxyl radical formation was measured with...
Comparison of the radical trapping ability of PBN, S-PPBN and NXY-059.Free Radic. Res. 34(4) , 417-26, (2001)
The nitrones alpha-phenyl-N-tert-butyl nitrone (PBN), sodium 2-sulfophenyl-N-tert-butyl nitrone (S-PBN) and disodium 2,4-disulfophenyl-N-tert-butyl nitrone (NXY-059) are neuroprotective in a variety o...