2,4-Pyrimidinediamine, 5-(4-chlorophenoxy)-6-methyl- (9CI)

Names

[ Name ]:
2,4-Pyrimidinediamine, 5-(4-chlorophenoxy)-6-methyl- (9CI)

[Synonym ]:
BW 48-210
5-(4-chloro-phenoxy)-6-methyl-pyrimidine-2,4-diyldiamine
5-(4-Chlorophenoxy)-6-methyl-2,4-pyrimidinediamine
5-(4-Chlor-phenoxy)-6-methyl-pyrimidin-2,4-diyldiamin
5-(p-Chlorophenoxy)-2,4-diamino-6-methylpyrimidine
2,4-Diamino-5-(4'-chlorophenoxy)-6-methylpyrimidine
2,4-Diamino-5-(p-chlorophenoxy)-6-methylpyrimidine

Chemical & Physical Properties

[ Density]:
1.398g/cm3

[ Boiling Point ]:
447.7ºC at 760 mmHg

[ Molecular Formula ]:
C₁₁H₁₁ClN₄O

[ Molecular Weight ]:
250.68400

[ Flash Point ]:
224.5ºC

[ Exact Mass ]:
250.06200

[ PSA ]:
87.05000

[ LogP ]:
3.55750

[ Index of Refraction ]:
1.671

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV8149800

CHEMICAL NAME :: Pyrimidine, 2,4-diamino-5-(p-chlorophenoxy)-6-methyl-

CAS REGISTRY NUMBER :: 7331-19-3

BEILSTEIN REFERENCE NO. :: 0252608

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C11-H11-Cl-N4-O

MOLECULAR WEIGHT :: 250.71

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 14XBAV "International Congress of Chemotherapy, Proceedings of the 3rd Congress, 1963," Kuemmerle, H.P., and Prezios, P., Stuttgart, Fed. Rep. Ger., Georg Thieme Verlag, 1964 Volume(issue)/page/year: -,367,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 6,185,1951