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Artepillin C

Names

[ CAS No. ]:
72944-19-5

[ Name ]:
Artepillin C

[Synonym ]:
3-[4-hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl]-2(E)-propenoic acid
3-{4-hydroxy-3,5-di-(3-methyl-2-butenyl)phenyl}-2(E)-propenoic acid
Artepillin C
3-[4-hydroxy-3,5-bis-(3-methyl-2-butenyl)phenyl]-2-propenic acid
artepillin
3-[4-hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl]-2-propenoic acid
(E)-3-{4-hydroxy-3,5-bis(3-methyl-2-butenyl)phenyl}-2-propenoic acid

Biological Activity

[Description]:

Artepillin C has gastroprotective, anti-inflammatory, antimicrobial, antioxidant, antitumor and choleretic activity. Artepillin C can be isolated from Brazilian green propolis[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Kobal MB,et al. Correlating Artepillin C cytotoxic activity on HEp-2 cells with bioinspired systems of plasma membranes. Mater Sci Eng C Mater Biol Appl. 2020 Jul;112:110943.  

[2]. Beserra FP, et al. Artepillin C as an outstanding phenolic compound of Brazilian green propolis for disease treatment: A review on pharmacological aspects. Phytother Res. 2020 Sep 15.  

Chemical & Physical Properties

[ Density]:
1.092g/cm3

[ Boiling Point ]:
447.672ºC at 760 mmHg

[ Molecular Formula ]:
C19H24O3

[ Molecular Weight ]:
300.39

[ Flash Point ]:
238.674ºC

[ Exact Mass ]:
300.17300

[ PSA ]:
57.53000

[ LogP ]:
4.50740

[ Index of Refraction ]:
1.586

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds