ici-118,551
Names
[ CAS No. ]:
72795-19-8
[ Name ]:
ici-118,551
[Synonym ]:
ICI 118,551 HYDROCHLORIDE
MFCD00153812
Ici 111,581
ICI-118-551 HYDROCHLORIDE HIGHLY SELECTI VE B2 A
Chemical & Physical Properties
[ Boiling Point ]:
439.3ºC at 760 mmHg
[ Molecular Formula ]:
C17H28ClNO2
[ Molecular Weight ]:
313.86300
[ Flash Point ]:
219.5ºC
[ Exact Mass ]:
313.18100
[ PSA ]:
41.49000
[ LogP ]:
3.80280
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Articles
Mol. Pharmacol. 35 , 295-303, (1989)
Prenalterol (beta 1-agonist), denopamine (beta 1-agonist), and zinterol (beta 2-agonist) were partial agonists of adenylate cyclase (AC) stimulation in human ventricular myocardium obtained from nonfa...
Species differences in the localization and number of CNS beta adrenergic receptors: rat versus guinea pig.J. Pharmacol. Exp. Ther. 249 , 911-920, (1989)
The localization and number of beta adrenergic receptors were directly compared in the brains of rats and guinea pigs. The time course of association and saturability of [125I]cyanopindolol (CYP) bind...
The pharmacology of a beta 2-selective adrenoceptor antagonist (ICI 118,551).J. Cardiovasc. Pharmacol. 5 , 430, (1983)
While specific antagonists of the beta 1-adrenoceptor, such as atenolol and betaxolol, are widely available, a potent specific antagonist selective for the beta 2-adrenoceptor has yet to be described....