Odorine

Names

[ Name ]:
Odorine

[Synonym ]:
Roxburghilin
(2R)-2-Methyl-N-{(2R)-1-[(2E)-3-phenyl-2-propenoyl]-2-pyrrolidinyl}butanamide
Butanamide, 2-methyl-N-[(2R)-1-[(2E)-1-oxo-3-phenyl-2-propen-1-yl]-2-pyrrolidinyl]-, (2R)-
Roxburghiline
Butanamide, 2-methyl-N-[1-[(2E)-1-oxo-3-phenyl-2-propen-1-yl]-2-pyrrolidinyl]-, (2R)-
2-Epiroxburghilin
(2R)-2-Methyl-N-{1-[(2E)-3-phenyl-2-propenoyl]-2-pyrrolidinyl}butanamide

Biological Activity

[Description]:

Odorine (Roxburghiline) is a natural product isolated from branches and leaves of Aglaia odorata. Odorine has potential antineoplastic activity and can inhibit both the initiation and promotion stages of skin cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. A Inad, et al. Cancer chemopreventive activity of odorine and odorinol from Aglaia odorata. Biol Pharm Bull. 2001 Nov;24(11):1282-5.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
551.3±40.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₂₄N₂O₂

[ Molecular Weight ]:
300.40

[ Flash Point ]:
287.2±27.3 °C

[ Exact Mass ]:
300.183777

[ PSA ]:
49.41000

[ LogP ]:
1.89

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.563

Safety Information

[ Hazard Codes ]:
Xi