1-Ethoxycarbonyl-beta-carboline

Names

[ Name ]:
1-Ethoxycarbonyl-beta-carboline

[Synonym ]:
1-ethoxycarbonyl-β-carboline
Kumujian A
ethyl 9H-pyrido[3,4-b]indole-1-carboxylate
ethyl β-carboline-1-carboxylate
Ethyl β-carboline-4-carboxylate
1-Ethoxycarbonyl-beta-carboline

Biological Activity

[Description]:

Kumujian A (1-Ethoxycarbonyl-β-carboline), an anti-inflammatory agent, inhibits both superoxide anion generation (IC50 = 4.87 μg/mL) and elastase release (IC50 = 6.29 μg/mL)[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[References]

[1]. Fang HW, et al. Total synthesis of cordatanine, structural reassignment of drymaritin, and anti-inflammatory activity of synthetic precursors. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3822-4.

Chemical & Physical Properties

[ Density]:
1.308±0.06 g/cm3 (20 ºC 760 Torr)

[ Melting Point ]:
145-146 ºC

[ Molecular Formula ]:
C₁₄H₁₂N₂O₂

[ Molecular Weight ]:
240.25700

[ Exact Mass ]:
240.09000

[ PSA ]:
54.98000

[ LogP ]:
2.89280

[ Water Solubility ]:
Practically insoluble (0.021 g/L) (25 ºC)

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.