(S)-pyrrolidine-3-carboxylic acid

[ Density]:
1.186

[ Boiling Point ]:
252 ºC

[ Melting Point ]:
185-191°C

[ Molecular Formula ]:
C₅H₉NO₂

[ Molecular Weight ]:
115.131

[ Flash Point ]:
106 ºC

[ Exact Mass ]:
115.063332

[ PSA ]:
49.33000

[ LogP ]:
-0.47

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.487

Click to get detail MSDS

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933990090

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Diastereocontrolled synthesis of enantioenriched 3,4-disubstituted beta-prolines.

J. Org. Chem. 72 , 398, (2007)

Enantioenriched 3,4-disubstituted beta-prolines have been prepared with a high diastereocontrol through a carbometalation reaction or through a domino Michael addition/carbometalation reaction.

Beta-proline analogues as agonists at the strychnine-sensitive glycine receptor.

J. Med. Chem. 35 , 233, (1992)

3-Carboxy-3,4-dehydropyrrolidine was found to bind with affinity equal to that of glycine in a [3H]strychnine binding assay. Simple substitution of the 1-, 2-, 4-, or 5-position resulted in marked los...

Endomorphin-1 analogues containing beta-proline are mu-opioid receptor agonists and display enhanced enzymatic hydrolysis resistance.

J. Med. Chem. 45(12) , 2571-8, (2002)

In this paper we describe the synthesis and affinity toward the mu-opioid receptor of some tetrapeptides obtained from endomorphin-1, H-Tyr-Pro-Trp-Phe-NH(2) (1), by substituting each amino acid in tu...

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