2-Methylquinoxaline

Names

[ Name ]:
2-Methylquinoxaline

[Synonym ]:
T66 BN ENJ C1
Quinoxaline,2-methyl
2-Methylquinoxaline,~
2-Methylquinoxaline
2-methylchinoxaline
2-methyl-quinoxalin
MFCD00006727
2-Methyl-chinoxalin
3-Methylquinoxaline
EINECS 230-664-9
Quinoxaline, 2-methyl-
methylquinoxaline,2-methylchinoxaline
2-Methylbenzopyrazine

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
243.9±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₈N₂

[ Molecular Weight ]:
144.173

[ Flash Point ]:
107.2±0.0 °C

[ Exact Mass ]:
144.068741

[ PSA ]:
25.78000

[ LogP ]:
1.76

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.633

[ Water Solubility ]:
miscible

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VD3450000

CHEMICAL NAME :: Quinoxaline, 2-methyl-

CAS REGISTRY NUMBER :: 7251-61-8

BEILSTEIN REFERENCE NO. :: 0113307

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H8-N2

MOLECULAR WEIGHT :: 144.19

WISWESSER LINE NOTATION :: T66 BN ENJ C1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 500 ug/plate

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 27,1954,1979

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
VD3450000

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Inhibitory effect of herbal medicines and their trapping abilities against methylglyoxal-derived advanced glycation end-products.

BMC Complement Altern. Med. 15 , 394, (2015)

Methylglyoxal (MG) is one of the most reactive glycating agents, which result the formation of advanced glycation end-products (AGEs) that have been implicated in the progression of age-related diseas...

2-(3-Aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides: a novel cluster of tumor-specific cytotoxins which reverse multidrug resistance.

Bioorg. Med. Chem. 17 , 3909-15, (2009)

A series of 2-(3-aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides 3a-l were prepared by condensation of various aryl aldehydes with 2-acetyl-3-methylquinoxaline-1,4-dioxide 2. These compounds inhibi...

Determination of methylglyoxal as 2-methylquinoxaline by high-performance liquid chromatography and its application to biological samples.

J. Chromatogr. A. 414(1) , 149-55, (1987)