Retrocyclin-1

Names

[ Name ]:
Retrocyclin-1

[Synonym ]:
cyclo(-gly-ile-cys-arg-cys-ile-cys-gly-arg-gly-ile-cys-arg-cys-ile-cys-gly-arg)
cyclo(-gly-ile-cys-arg-cys-ile-cys-gly-arg-gly-ile-cys-arg-cys-ile-cys-gly-arg),(disulfide bonds between cys3 and cys16/cys5 and cys14/cys7 and cys12)
rc-100

Biological Activity

[Description]:

Retrocyclin-1 is a kind of Theta-defensin. Retrocyclin-1 recognizes and binds to carbohydrate-containing surface molecules, to protect cells from HIV-1 infection. Retrocyclin-1 exhibits high affinity to fetuin, gp120 (Kd=35.4 nM), CD4 (Kd=31 nM), and galactosylceramide (Kd=24.1 nM)[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Molecular Formula ]:
C₇₄H₁₂₈N₃₀O₁₈S₆

[ Molecular Weight ]:
1918.39

[ Exact Mass ]:
1916.83000

[ PSA ]:
923.20000

[ LogP ]:
2.35660

Related Compounds

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