1-Palmitoyl-sn-glycerol 3-phosphate

Names

[ CAS No. ]:
7220-34-0

[ Name ]:
1-Palmitoyl-sn-glycerol 3-phosphate

[Synonym ]:
palmitoyl lysophosphatidic acid
1-Palmitoylglycerol 3-phosphate
lysophosphatidic acid
1-O-palmitoyl-3-O-phosphoryl-sn-glycerol
1-palmitoyl-2-lyso-sn-glycero-3-phosphatidic acid
1-oleoyl-2-hydroxy-sn-glycero-3-phosphate
1-Palmitoyl lysophosphatidate
1-Palmitoyllysophosphatidic acid
1-hexadecanoyl-phosphatidic acid
(R)-2-hydroxy-3-(phosphonooxy)propyl palmitate
1-Hexadecanoyl-sn-glycero-3-phosphate
(2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate

Biological Activity

[Description]:

1-Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) is an endogenous metabolite. 1-Palmitoyl-sn-glycerol 3-phosphate can be used for the research of non‐alcoholic fatty liver disease[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[References]

[1]. Chalasani N, et al. Randomised clinical trial: a leucine-metformin-sildenafil combination (NS-0200) vs placebo in patients with non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2018 Jun;47(12):1639-1651.  

Chemical & Physical Properties

[ Molecular Formula ]:
C19H39O7P

[ Molecular Weight ]:
410.48

[ Exact Mass ]:
432.22500

[ PSA ]:
125.93000

[ LogP ]:
4.91930

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream