Thielavin B

Names

[ CAS No. ]:
71950-67-9

[ Name ]:
Thielavin B

[Synonym ]:
Benzoic acid,4-((2,4-dihydroxy-3,6-dimethylbenzoyl)oxy)-2-methoxy-3,5,6-trimethyl-,4-carboxy-3-methoxy-2,5,6-trimethylphenyl ester
4-({4-[(2,4-dihydroxy-3,6-dimethylbenzoyl)oxy]-2-methoxy-3,5,6-trimethylbenzoyl}oxy)-2-methoxy-3,5,6-trimethylbenzoic acid
Thielavin B

Biological Activity

[Description]:

Thielavin B is an inhibitor of prostaglandin biosynthesis produced by Thielavia terricola. Thielavin B effectively influences the prostaglandin E2 synthesis from the endoperoxide. Thielavin B is significantly effective on carrageenan-induced oedema of rats when administered intravenously[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Research Areas >> Endocrinology

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

[References]

[1]. Kitahara N, et al. Thielavin A and B, new inhibitors of prostaglandin biosynthesis produced by Thielavia terricola. J Antibiot (Tokyo). 1981;34(12):1562-1568.

Chemical & Physical Properties

[ Density]:
1.276g/cm3

[ Boiling Point ]:
807.5ºC at 760 mmHg

[ Molecular Formula ]:
C₃₁H₃₄O₁₀

[ Molecular Weight ]:
566.59600

[ Flash Point ]:
261.1ºC

[ Exact Mass ]:
566.21500

[ PSA ]:
148.82000

[ LogP ]:
5.71880

[ Index of Refraction ]:
1.601

Related Compounds

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