Prostaglandin D3

Names

[ CAS No. ]:
71902-47-1

[ Name ]:
Prostaglandin D3

[Synonym ]:
9S,15S-dihydroxy-11-oxo-5Z,13E,17Z-prostatrienoic acid
PGD3
Prosta-5,13,17-trien-1-oic acid, 9,15-dihydroxy-11-oxo-, (5Z,9α,13E,15S,17Z)-
Prostaglandin D3
(5Z,9α,13E,15S,17Z)-9,15-Dihydroxy-11-oxoprosta-5,13,17-trien-1-oic acid
(Z)-7-[(1R,2R,5S)-5-hydroxy-2-[(1E,3S,5Z)-3-hydroxyocta-1,5-dienyl]-3-oxocyclopentyl]hept-5-enoic acid

Biological Activity

[Description]:

Prostaglandin D3 (PGD3) is a prostaglandin that acts as an inhibitor of platelet aggregation and a modulator of autonomic neurotransmission in humans[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor

[References]

[1]. M O Whitaker, et al. Triene prostaglandins: prostaglandin D3 and icosapentaenoic acid as potential antithrombotic substances. Proc Natl Acad Sci U S A. 1979 Nov;76(11):5919-23.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
561.2±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₃₀O₅

[ Molecular Weight ]:
350.45

[ Flash Point ]:
307.2±26.6 °C

[ Exact Mass ]:
350.209320

[ PSA ]:
94.83000

[ LogP ]:
1.57

[ Vapour Pressure ]:
0.0±3.5 mmHg at 25°C

[ Index of Refraction ]:
1.575

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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