2-Amino-4-hydroxypteridine-6-carbaldehyde

Names

[ CAS No. ]:
712-30-1

[ Name ]:
2-Amino-4-hydroxypteridine-6-carbaldehyde

[Synonym ]:
2-amino-4-oxo-1H-pteridine-6-carbaldehyde
formylpterin
2-amino-4-hydroxy-6-pteridylcarboxaldehyde
6-pteridinecarboxaldehyde, 2-amino-4-hydroxy-
6-formyl-pterin
6-Pteridinecarboxaldehyde, 2-amino-3,4-dihydro-4-oxo-
2-amino-4-oxo-3,4-dihydro-pteridine-6-carbaldehyde
Pterin-6-aldehyde
2-Amino-4-hydroxy-6-formylpteridine
2-Amino-4-hydroxypteridine-6-carbaldehyde
2-Amino-4-oxo-1,4-dihydro-6-pteridinecarbaldehyde
2-AMINO-6-FORMYLPTERIDIN-4-ONE
2-amino-3,4-dihydro-4-oxo-6-pteridinecarboxaldehyde
6-Pterinaldehyde
2-amino-4-hydroxypteridine-6-carboxaldehyde

Biological Activity

[Description]:

6-Formylpterin is an inhibitor of Xanthine Oxidase. 6-Formylpterin induces intracellular ROS generation and apoptosis in HL-60 cells. 6-Formylpterin suppresses cell proliferation in PanC-1 cells[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Metabolic Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Xanthine Oxidase

[References]

[1]. Arai T, et al. 6-formylpterin, a xanthine oxidase inhibitor, intracellularly generates reactive oxygen species involved in apoptosis and cell proliferation. Free Radic Biol Med. 2001 Feb 1;30(3):248-59.

Chemical & Physical Properties

[ Density]:
1.9±0.1 g/cm3

[ Boiling Point ]:
489.1ºC at 760 mmHg

[ Molecular Formula ]:
C₇H₅N₅O₂

[ Molecular Weight ]:
191.15

[ Flash Point ]:
249.6ºC

[ Exact Mass ]:
191.044327

[ PSA ]:
114.88000

[ LogP ]:
-1.77

[ Index of Refraction ]:
1.893

Safety Information

[ HS Code ]:
2933990090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%