<Suppliers Price>

Carbodine

Names

[ CAS No. ]:
71184-20-8

[ Name ]:
Carbodine

[Synonym ]:
2-Hydroxy-5-(1,1,3,3-tetramethylbutyl)benzenesulfonic acid
p-Isooctylphenol-2-sulfonic acid
D-(-)-carbodine
Benzenesulfonic acid,2-hydroxy-5-(1,1,3,3-tetramethylbutyl)
(-)-carbodine
(1R,2S,3R,4R)-1-[2,3-dihydroxy-4-(hydroxymethyl)-cyclopentan-1-yl]cytosine

Biological Activity

[Description]:

Carbodine (Carbocyclic cytidine) is a broad-spectrum antiviral agent active against DNA viruses, (+)RNA viruses, (-)RNA viruses, paramyxo, rhabdo and (+/-)RNA viruses, targets CTP synthetase that converts UTP to CTP. Carbodine (Carbocyclic cytidine) possesses significant antiviral activity against influenza virus types A0/PR-8/34 and A2/Aichi/2/68 in vitro[1][2].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus
Research Areas >> Infection

[References]

[1]. De Clercq E, et al. Broad-spectrum antiviral activity of carbodine, the carbocyclic analogue of cytidine. Biochem Pharmacol. 1990 Jan 15;39(2):319-25.

[2]. Shannon WM, et al. Evaluation of carbodine, the carbocyclic analog of cytidine, and related carbocyclic analogs of pyrimidine nucleosides for antiviral activity against human influenza Type A viruses. Antimicrob Agents Chemother. 1981 Dec;20(6):769-76.

Chemical & Physical Properties

[ Density]:
1.74g/cm3

[ Boiling Point ]:
477ºC at 760 mmHg

[ Molecular Formula ]:
C10H15N3O4

[ Molecular Weight ]:
286.38700

[ Flash Point ]:
242.3ºC

[ Exact Mass ]:
286.12400

[ PSA ]:
82.98000

[ LogP ]:
4.43350

[ Index of Refraction ]:
1.743

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds