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L-Cysteine hydrochloride hydrate

Names

[ CAS No. ]:
7048-04-6

[ Name ]:
L-Cysteine hydrochloride hydrate

[Synonym ]:
L-cysteine monohydrate hydrochloride
(1R)-1-Carboxy-2-sulfanylethanaminium chloride hydrate (1:1:1)
D,L-cis-2-Aminocyclopentanol-Hydrochlorid
H-Cys-OH.HCl.H2O
L-(+)-cysteine hydrochloride hydrate
(1R,2S)-CIS-2-AMINOCYCLOPENTANOL HYDROCHLORIDE
L-cysteine monohydrochloride monohydrate
(R)-cysteine hydrochloride monohydrate
MFCD00065606
L-Cysteine hydrochloride hydrate
(2R)-2-Amino-3-sulfanylpropanoic acid hydrate hydrochloride
(R)-2-Amino-3-mercaptopropanoic acid hydrochloride hydrate
Trans-(1R,2S)-2-Aminocyclopentanol Hydrochloride
EINECS 200-157-7
D,L-cysteine hydrochloride monohydrate
SH1YZVQ &&HCl H2O
L-cysteine HCl monohydrate
L-Cysteine, hydrochloride, hydrate (1:1:1)
(R)-(+)-Cysteine hydrochloride hydrate
(1R,2S)-2-aMinocyclopentan-1-ol hydrochloride
L-Cysteine hydrochloride monohydrate
L-Cysteine monohydrate monochloride
L-Cysteinehydrochloridemonohydrate
H-Cys-OH·HCl·H2O
(+-)-cis-2-amino-cyclopentanol,hydrochloride
L-Cysteine Hydrochloride

Biological Activity

[Description]:

L-Cysteine hydrochloride hydrate is a conditionally essential amino acid, which acts as a precursor for biologically active molecules such as hydrogen sulphide (H2S), glutathione and taurine. L-Cysteine hydrochloride hydrate suppresses ghrelin and reduces appetite in rodents and humans[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. McGavigan AK, et al. L-cysteine suppresses ghrelin and reduces appetite in rodents and humans. Int J Obes (Lond). 2015 Mar;39(3):447-55.

Chemical & Physical Properties

[ Boiling Point ]:
293.9ºC at 760 mmHg

[ Melting Point ]:
175°C

[ Molecular Formula ]:
C3H10ClNO3S

[ Molecular Weight ]:
175.634

[ Flash Point ]:
131.5ºC

[ Exact Mass ]:
175.006989

[ PSA ]:
111.35000

[ LogP ]:
0.76610

[ Index of Refraction ]:
6 ° (C=8, 1mol/L HCl)

[ Storage condition ]:
Store at RT.

[ Stability ]:
Stable. Incompatible with strong oxidizing agents, most common metals, hydrogen chloride.

[ Water Solubility ]:
H2O: 1 M at 20 °C, clear, colorless

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HA2285000
CHEMICAL NAME :
L-Cysteine, hydrochloride, monohydrate
CAS REGISTRY NUMBER :
7048-04-6
LAST UPDATED :
199504
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C3-H7-N-O2-S.Cl-H.H2-O
MOLECULAR WEIGHT :
175.65

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3564 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JJANAX Japanese Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo 141, Japan) V.21- 1968- Volume(issue)/page/year: 41,105,1988 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9440 No. of Facilities: 196 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 1414 (estimated) No. of Female Employees: 879 (estimated)

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
HA2285000

[ HS Code ]:
29309013

Precursor & DownStream

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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