Prifelone

Names

[ Name ]:
Prifelone

[Synonym ]:
Prifelona [INN-Spanish]
2,6-di-tert-butyl-4-(2'-thenoyl)phenol
(3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl)-2-thienylmethanone
(3,5-di-tert-butyl-4-hydroxy-phenyl)-thiophen-2-yl-methanone
R-830T
Prifelonum [INN-Latin]
Prifelone
R 830

Biological Activity

[Description]:

Prifelone (R 830; R 830T; S 16820) is a di-tert-butylphenol with anti-inflammatory and antioxidant activity. Prifelone inhibits guinea pig lung oxygenase and bovine seminal vesicle cyclooxygenase[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> COX

[References]

[1]. Moore GG, et al. 2,6-Di-tert-butyl-4-(2'-thenoyl)phenol(R-830): a novel nonsteroidal anti-inflammatory agent with antioxidant properties. Agents Actions. 1982 Dec;12(5-6):674-83.

Chemical & Physical Properties

[ Density]:
1.095g/cm3

[ Boiling Point ]:
422ºC at 760 mmHg

[ Molecular Formula ]:
C₁₉H₂₄O₂S

[ Molecular Weight ]:
316.45800

[ Flash Point ]:
209ºC

[ Exact Mass ]:
316.15000

[ PSA ]:
65.54000

[ LogP ]:
5.27970

[ Index of Refraction ]:
1.557

Synthetic Route

Click to get detail synthetic route

Related Compounds

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