4-[5-(2-oxohexahydrothieno[3,4-d]imidazol-6-yl)pentanoylamino]benzoic acid

Names

[ CAS No. ]:
6929-40-4

[ Name ]:
4-[5-(2-oxohexahydrothieno[3,4-d]imidazol-6-yl)pentanoylamino]benzoic acid

[Synonym ]:
(N)-(+)-BIOTINYL-4-AMINOBENZOIC ACID
N-(+)-Biotinyl-4-aminobenzoic acid

Chemical & Physical Properties

[ Melting Point ]:
295-297 °C

[ Molecular Formula ]:
C₁₇H₂₁N₃O₄S

[ Molecular Weight ]:
363.43100

[ Exact Mass ]:
363.12500

[ PSA ]:
132.83000

[ LogP ]:
2.77970

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

Articles

Neonatal screening for biotinidase deficiency.

Ann. Clin. Lab. Sci. 22 , 144-154, (1992)

Children with juvenile-onset multiple carboxylase deficiency lack biotinidase activity (biotinamide amidohydrolase, EC 3.5.1.12) in the liver and other tissues. Hence, little free biotin is metabolica...

Determination of biotinidase activity by liquid chromatography with fluorimetric detection.

J. Chromatogr. A. 383 , 148, (1986)

Purification of biotinidase from human plasma and its activity on biotinyl peptides.

Biochemistry 24 , 2471, (1985)

Biotinidase catalyzes the hydrolysis of N epsilon-biotinyllysine (biocytin) to form biotin and free lysine. The enzyme has been purified 4800-fold from outdated human plasma and was determined by sodi...