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GAMMA-LUMICOLCHICINE

Names

[ CAS No. ]:
6901-14-0

[ Name ]:
GAMMA-LUMICOLCHICINE

[Synonym ]:
(7bS)-7c-Acetylamino-1,2,3,9-tetramethoxy-(7br,10ac)-6,7,7b,10a-tetrahydro-5H-benzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-8-on
Einecs 230-009-7
[7S-(7alpha,7balpha,10aalpha)]-N-(5,6,7,7b,8,10a-hexahydro-1,2,3,9-tetramethoxy-8-oxobenzo[a]cyclopenta[3,4]cyclobuta[1,2-c]cyclohepten-7-yl)acetamide
g-Lumicolchicine

Biological Activity

[Description]:

γ-Lumicolchicine is an inactive analogue of Colchicine (HY-16569)[1]

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Farroni JS, McCool BA. Extrinsic factors regulate partial agonist efficacy of strychnine-sensitive glycine receptors. BMC Pharmacol. 2004 Aug 9;4:16.  

Chemical & Physical Properties

[ Density]:
1.3g/cm3

[ Boiling Point ]:
623.2ºC at 760 mmHg

[ Melting Point ]:
268ºC

[ Molecular Formula ]:
C22H25NO6

[ Molecular Weight ]:
399.43700

[ Flash Point ]:
330.7ºC

[ Exact Mass ]:
399.16800

[ PSA ]:
83.09000

[ LogP ]:
2.66680

[ Index of Refraction ]:
1.596

Safety Information

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ WGK Germany ]:
3

Synthetic Route


Related Compounds