N-[2-(4-sulfamoylphenyl)ethyl]-2-thiophen-2-ylquinoline-4-carboxamide

Names

[ Name ]:
N-[2-(4-sulfamoylphenyl)ethyl]-2-thiophen-2-ylquinoline-4-carboxamide

[Synonym ]:
MFCD05999926
4-Quinolinecarboxamide, N-[2-[4-(aminosulfonyl)phenyl]ethyl]-2-(2-thienyl)-
N-[2-(4-Sulfamoylphenyl)ethyl]-2-(2-thienyl)quinoline-4-carboxamide
N-[2-(4-Sulfamoylphenyl)ethyl]-2-(2-thienyl)-4-quinolinecarboxamide

Biological Activity

[Description]:

ROS kinases-IN-2 is a ROS kinase inhibitor with 21.53% inhibition at 10 μM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> ROS

[Target]

ROS[1]

[References]

[1]. Dorre A. GRUENEBERG, et al. Novel methods, compounds, and compositions for inhibition of ros. Patent WO2014141129A2.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₂₂H₁₉N₃O₃S₂

[ Molecular Weight ]:
437.535

[ Exact Mass ]:
437.086792

[ LogP ]:
2.70

[ Index of Refraction ]:
1.677

[ Storage condition ]:
2-8°C