eupatoriopicrine

Names

[ Name ]:
eupatoriopicrine

[Synonym ]:
6α-[Hydroxy-8β-(4-Hydroxy-2-hydroxymethyl-trans-crotonoyloxy)-germacra-1(10)t,4t,11(13)-trien-12-saeure-6-lacton
(E)-4-Hydroxy-2-hydroxymethyl-but-2-enoic acid (6E,10E)-(3aR,4R,11aR)-6,10-dimethyl-3-methylene-2-oxo-2,3,3a,4,5,8,9,11a-octahydro-cyclodeca[b]furan-4-yl ester
6α-[hydroxy-8β-(4-hydroxy-2-hydroxymethyl-trans-crotonoyloxy)-germacra-1(10)t,4t,11(13)-trien-12-oic acid-6-lactone

Biological Activity

[Description]:

Eupatoriopicrin is an antitrypanosomic agent with an IC50 value of 1.2 μM (T. b. rhodesiense). Eupatoriopicrin is cytotoxic to L6 cells with an IC50 value of 1.6 μM[1].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Julianti T, et a. Antitrypanosomal sesquiterpene lactones from Saussurea costus. Fitoterapia. 2011 Oct;82(7):955-9.

Chemical & Physical Properties

[ Density]:
1.1481 (rough estimate)

[ Boiling Point ]:
414.03°C (rough estimate)

[ Molecular Formula ]:
C₂₀H₂₆O₆

[ Molecular Weight ]:
362.42

[ Exact Mass ]:
362.17300

[ PSA ]:
93.06000

[ LogP ]:
1.98350

[ Index of Refraction ]:
1.4450 (estimate)

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.