<Suppliers Price>

Isocucurbitacin D

Names

[ CAS No. ]:
68422-20-8

[ Name ]:
Isocucurbitacin D

[Synonym ]:
3-epi-isocucurbitacin D
(3S,8S,9R,10R,13R,14S,16R,17R)-17-((E)-(R)-1,5-Dihydroxy-1,5-dimethyl-2-oxo-hex-3-enyl)-3,16-dihydroxy-4,4,9,13,14-pentamethyl-3,4,7,8,9,10,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-2,11-dione
iso-cucurbitacin D
Isocucurbitacin D
isocucurbitacin D

Biological Activity

[Description]:

Isocucurbitacin D is an antitumor agent[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

Isocucurbitacin D 抑制癌细胞生长,对 SK-MEL-2、A549、XF498、HCT15 和 SK-OV-3 细胞的 ED50 分别为 0.06、0.2、0.6、0.8 和 1.2 μg/mL[1]。 Cell Proliferation Assay[1] Cell Line: MCF-7, MDA MB 231, A2780, A2780 CP, HepG2 and HCT-116 cells Concentration: 0-100 μM Incubation Time: 48 h Result: Inhibited cell proliferation with IC50s of 12.0, 30.7, 37.8, 47.9, >100 and >100 μM against MDA MB 231, HCT-116, HepG2, MCF-7, A2780 and A2780 CP, respectively.

[References]

[1]. Ryu S Y, et al. Antitumor activity of Trichosanthes kirilowii. Archives of Pharmacal Research, 1994, 17: 348-353.

Chemical & Physical Properties

[ Molecular Formula ]:
C30H44O7

[ Molecular Weight ]:
516.66600

[ Exact Mass ]:
516.30900

[ PSA ]:
132.13000

[ LogP ]:
2.92850


Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.