2-Propenamide, N-methyl-3-(5,10,11,11a-tetrahydro-9-hydroxy-11-methoxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-
Names
[ CAS No. ]:
68373-95-5
[ Name ]:
2-Propenamide, N-methyl-3-(5,10,11,11a-tetrahydro-9-hydroxy-11-methoxy-8-methyl-5-oxo-1H-pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-
[Synonym ]:
Mazethramycin B
(+)-N-Methyl-3-(5,10,11,11a-tetrahydro-9-hydroxy-11-methoxy-8-methyl-5-oxo-1H-pyrrolo[2,1-c][1,4]benzodiazepine-2-yl)propenamide
Chemical & Physical Properties
[ Density]:
1.34g/cm3
[ Boiling Point ]:
631.9ºC at 760 mmHg
[ Molecular Formula ]:
C18H21N3O4
[ Molecular Weight ]:
343.37700
[ Flash Point ]:
335.9ºC
[ Exact Mass ]:
343.15300
[ PSA ]:
90.90000
[ LogP ]:
1.96600
[ Index of Refraction ]:
1.646
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UC6475920
- CHEMICAL NAME :
- 2-Propenamide, N-methyl-3-(5,10,11,11a-tetrahydro-9-hydroxy-11-metho xy-8-methyl-5-oxo-1H- pyrrolo(2,1-c)(1,4)benzodiazepin-2-yl)-
- CAS REGISTRY NUMBER :
- 68373-95-5
- LAST UPDATED :
- 199212
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C18-H21-N3-O4
- MOLECULAR WEIGHT :
- 343.42
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 800 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 33,665,1980