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Isosulfan blue

Names

[ CAS No. ]:
68238-36-8

[ Name ]:
Isosulfan blue

[Synonym ]:
Isosulfan blue [USAN]
ISOSULFAN BLUE
Disulphin Blau
Sulphan Blue
Sulphan blue 2,5-disulfophenyl isomer
Patentblau V
Sulfanblau
UNII-39N9K8S2A4

Biological Activity

[Description]:

Isosulfan blue is a blue dye for the identification of lymph vessels during lymphangiography. Isosulfan blueis is used during sentinel lymph node biopsies in breast cancer. Isosulfan blue is possible to have an allergic reaction during breast cancer operations[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

Isosulfan blue can rapidly uptake into lymph tissue with little diffusion to other surrounding tissues[1].

[References]

[1]. Efron P, et al. Anaphylactic reaction to isosulfan blue used for sentinel node biopsy: case report and literature review. Breast J. 2002 Nov-Dec;8(6):396-9.

[2]. Laurie SA, et al. Anaphylaxis to isosulfan blue. Ann Allergy Asthma Immunol. 2002 Jan;88(1):64-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C27H31N2NaO6S2

[ Molecular Weight ]:
569.68800

[ Exact Mass ]:
569.17600

[ PSA ]:
134.58000

[ LogP ]:
6.21260

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds