11-Dehydro-thromboxane B2

Names

[ Name ]:
11-Dehydro-thromboxane B2

[Synonym ]:
11-Dehydro Thromboxane B2
7-{(2R,3S,4S)-4-Hydroxy-2-[(3S)-3-hydroxy-1-octen-1-yl]-6-oxotetrahydro-2H-pyran-3-yl}-5-heptenoic acid

Biological Activity

[Description]:

11-Dehydro-thromboxane B2 is a platelet hemagglutinin. Thromboxane inhibition was assessed by urinary excretion levels of 11-Dehydro-thromboxane B2. 11-Dehydro-thromboxane B2 can be used in the study of atherosclerotic thrombosis[1][2].

[Related Catalog]:

Research Areas >> Metabolic Disease

[Target]

Human Endogenous Metabolite

[References]

[1]. Simeone P, et al. Significance of urinary 11-dehydro-thromboxane B2 in age-related diseases: Focus on atherothrombosis. Ageing Res Rev. 2018 Dec;48:51-78.

[2]. Lopez LR, et al. Platelet thromboxane (11-dehydro-Thromboxane B2) and aspirin response in patients with diabetes and coronary artery disease. World J Diabetes. 2014 Apr 15;5(2):115-27.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
588.5±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₃₂O₆

[ Molecular Weight ]:
368.46

[ Flash Point ]:
202.9±23.6 °C

[ Exact Mass ]:
368.219879

[ PSA ]:
104.06000

[ LogP ]:
1.92

[ Vapour Pressure ]:
0.0±3.7 mmHg at 25°C

[ Index of Refraction ]:
1.552

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.