AST 7062601

Names

[ Name ]:
AST 7062601

Biological Activity

[Description]:

AST 7062601 (AST070) is a Ucp1 inducer that strongly induces endogenous Ucp1 expression in primary mouse brown adipocytes. Ucp1 refers to uncoupling protein, found in brown and beige fat cells. In mammals, UCP1 oxidizes fatty acids and uncouples ATP production in mitochondria to promote energy dissipation as heat. AST 7062601 can be used to study thermogenic, uncoupled respiration[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[Target]

Ucp1[1]

[References]

[1]. Vergnes L, et al. Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation. J Biol Chem. 2020 Oct 30;295(44):15054-15069.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₅N₃O₄S

[ Molecular Weight ]:
369.39

Related Compounds

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