4-Phenoxybenzaldehyde
Names
[ CAS No. ]:
67-36-7
[ Name ]:
4-Phenoxybenzaldehyde
[Synonym ]:
VHR DOR
4-Formyldiphenyl ether
p-Phenoxybenzaldehyde
4-PhOC6H4-CHO
4-phenyloxybenzaldehyde
MFCD00003383
Benzaldehyde, 4-phenoxy-
Benzaldehyde,4-phenoxy
para-phenoxy benzaldehyde
4-OPhC6H4CHO
4-Phenoxybenzaldehyde
4-Phenoxy-benzaldehyde
EINECS 200-650-7
Benzaldehyde,p-phenoxy
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
320.1±25.0 °C at 760 mmHg
[ Melting Point ]:
24-25 °C(lit.)
[ Molecular Formula ]:
C13H10O2
[ Molecular Weight ]:
198.217
[ Flash Point ]:
144.7±16.7 °C
[ Exact Mass ]:
198.068085
[ PSA ]:
26.30000
[ LogP ]:
3.84
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.609
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CU7560000
- CHEMICAL NAME :
- Benzaldehyde, p-phenoxy-
- CAS REGISTRY NUMBER :
- 67-36-7
- BEILSTEIN REFERENCE NO. :
- 1947841
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C13-H10-O2
- MOLECULAR WEIGHT :
- 198.23
- WISWESSER LINE NOTATION :
- VHR DOR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 190 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 19,964,1964
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
Xi
[ Safety Phrases ]:
S23-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
CU7560000
[ HS Code ]:
2912499000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2912499000
[ Summary ]:
2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
Bioorg. Med. Chem. Lett. 22 , 649-52, (2012)
A series of structurally novel, substituted 2-(2-(4-aryloxybenzylidene) hydrazinyl)benzothiazole derivatives incorporating 2-hydrazinyl benzothiazole and 4-(aryloxy)benzaldehyde were designed and synt...
Spirodiketopiperazine-based CCR5 antagonists: Lead optimization from biologically active metabolite.Bioorg. Med. Chem. Lett. 17(3) , 727-31, (2007)
Hydroxylated derivatives were designed and synthesized based on the information of oxidative metabolites. Compounds derived from beta-substituted (2R,3R)-2-amino-3-hydroxypropionic acid showed improve...
Novel non-benzimidazole chk2 kinase inhibitors.Bioorg. Med. Chem. Lett. 16(7) , 1924-8, (2006)
In a recent paper, [Arienti, K. L.; Brunmark, A.; Axe, F. U.; McClure, K. M.; Lee, A.; Blevitt, J.; Neff, D. K.; Huang, L.; Crawford, S.; Chennagiri, R. P.; Karlsson, L.; Brietenbucher, J. G. J. Med. ...