4-(Boc-amino)benzoic acid

Names

[ Name ]:
4-(Boc-amino)benzoic acid

[Synonym ]:
4-[(tert-butoxycarbonyl)amino]benzoic acid
MFCD00037428
Benzoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-
4-(Boc-amino)benzoic Acid
N-Boc-p-aminobenzoic acid
4-(t-butyloxycarbonylamino)-benzoic acid
N-tert-butoxycarbonyl-para-aminobenzoic acid
4-({[(2-Methyl-2-propanyl)oxy]carbonyl}amino)benzoic acid
N-Boc-4-aminobenzoic acid
Boc-4-amino benzoic acid
Boc-4-Abz-OH

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
336.2±25.0 °C at 760 mmHg

[ Melting Point ]:
200ºC

[ Molecular Formula ]:
C₁₂H₁₅NO₄

[ Molecular Weight ]:
237.252

[ Flash Point ]:
157.1±23.2 °C

[ Exact Mass ]:
237.100113

[ PSA ]:
75.63000

[ LogP ]:
3.11

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.575

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Structure-activity relationships of a series of substituted benzamides: potent D2/5-HT2 antagonists and 5-HT1a agonists as neuroleptic agents.

J. Med. Chem. 39 , 1172, (1996)

A series of substituted (4-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)butyl)benzamide derivatives was prepared and evaluated as potential atypical antipsychotic agents. The target compounds were readi...