ethyl 2-[4-[(6-chlorobenzothiazol-2-yl)oxy]phenoxy]propionate
Names
[ CAS No. ]:
66441-11-0
[ Name ]:
ethyl 2-[4-[(6-chlorobenzothiazol-2-yl)oxy]phenoxy]propionate
[Synonym ]:
2-[4-(6-chloro-benzothiazol-2-yloxy)-phenoxy]-propionic acid ethyl ester
ethyl (RS)-2-[4-(6-chlorobenzothiazol-2-yloxy)phenoxy]propionate
Ethyl 2-{4-[(6-chloro-1,3-benzothiazol-2-yl)oxy]phenoxy}propanoat e
Tienoxolol
D-(+)-2-[4-(6-chloro-2-benzothiazolyloxy)-phenoxy]-propionic acid ethyl ester
ethyl 2-[4-[(6-chloro-2-benzothiazolyl)oxy]phenoxy]propanoate
ethyl 2-(4-(6-chlorobenzothiazol-2-yloxy)-phenoxy)-propionate
ethyl (RS)-2-[4-(6-chloro-1,3-benzothiazol-2-yloxy)phenoxy]propionate
Tienoxololum [Latin]
ethyl 2-{p-[(6-chloro-2-benzothiazolyl)oxy]phenoxy}propionate
ethyl 2-<3-<(1,1-dimethylethyl)amino>-2-hydroxypropoxy>-5-<(2-thienylcarbonyl)amino>benzoate
(+-)-Ethyl 2-(3-(tert-butylamino)-2-hydroxypropoxy)-5-(2-thiophenecarboxamido)benzoate
Tienoxololum
rac-ethyl (2R)-2-{4-[(6-chloro-1,3-benzothiazol-2-yl)oxy]phenoxy}propanoate
ethyl 2-(4-(6-chlorobenzthiazol-2-yloxy)-phenoxy)-propionate
2-[4-(6-chloro-2-benzothiazolyloxy)-phenoxy]-propanoic acid ethyl ester
Chemical & Physical Properties
[ Density]:
1.336g/cm3
[ Boiling Point ]:
497.7ºC at 760 mmHg
[ Molecular Formula ]:
C18H16ClNO4S
[ Molecular Weight ]:
377.84200
[ Flash Point ]:
254.8ºC
[ Exact Mass ]:
377.04900
[ PSA ]:
85.89000
[ LogP ]:
5.07240
[ Index of Refraction ]:
1.616
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UA2452000
- CHEMICAL NAME :
- Propanoic acid, 2-(4-((6-chloro-2-benzothiazolyl)oxy)phenoxy)-, ethyl ester
- CAS REGISTRY NUMBER :
- 66441-11-0
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C18-H16-Cl-N-O4-S
- MOLECULAR WEIGHT :
- 377.86
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 907 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 36(7),40,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1101,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2853 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 36(7),40,1992
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 619 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity) Behavioral - tremor
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 36(7),40,1992