2,5-Dichloro-4-nitroaniline

Names

[ Name ]:
2,5-Dichloro-4-nitroaniline

[Synonym ]:
ANILINE,2,5-DICHLORO-4-NITRO
2,5-dichloro-4-nitrophenylamine
2,5-Dichloro-4-nitro aniline
1-amino-2,5-dichloro-4-nitrobenzene
Benzenamine,2,5-dichloro-4-nitro
2,5-Dichloro-4-nitroaniline
2,5-dichloro-4-nitrobenzeneamine
2,5-dichloro-p-nitroaniline
2,5-dichloro-4-aminonitrobenzene
MFCD00025157
Benzenamine, 2,5-dichloro-4-nitro-
EINECS 229-591-5

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
361.1±37.0 °C at 760 mmHg

[ Melting Point ]:
154-158 °C(lit.)

[ Molecular Formula ]:
C₆H₄Cl₂N₂O₂

[ Molecular Weight ]:
207.014

[ Flash Point ]:
172.2±26.5 °C

[ Exact Mass ]:
205.964981

[ PSA ]:
71.84000

[ LogP ]:
3.06

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.656

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BX2950000

CHEMICAL NAME :: Aniline, 2,5-dichloro-4-nitro-

CAS REGISTRY NUMBER :: 6627-34-5

BEILSTEIN REFERENCE NO. :: 2211952

LAST UPDATED :: 199710

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C6-H4-Cl2-N2-O2

MOLECULAR WEIGHT :: 207.02

WISWESSER LINE NOTATION :: ZR BG EG DNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2820 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,599,1986

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
2811

[ WGK Germany ]:
3

[ RTECS ]:
BX2950000

[ HS Code ]:
2921420090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2921420090

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Probing the acidity of carboxylic acids in protic ionic liquids, water, and their binary mixtures: activation energy of proton transfer.

.PubMed ID

Acidity functions were used to express the ability of a solvent/solution to donate/accept a proton to a solute. The present work accounts for the acidity determination of HCOOH, CH3COOH, and CH3CH2COO...

A redetermination and extension of the H 0 scale of acidity in aqueous perchloric acid. Yates K and Wai H.

J. Am. Chem. Soc.

Solvent Effects in Organic Chemistry. II. Sulfolane1--A Weakly Basic Aprotic Solvent of High Dielectric Constant2. Arnett EM and Douty CF.

J. Am. Chem. Soc. 86(3) , 409-412, (1964)